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Faculty

Dr. Surabhi Sonam
Associate Professor (Head of Department)
Dr. Surabhi Sonam
Dr. Surabhi Sonam
Associate Professor (Head of Department)
Specialization
Specialization
  • Mechanobiology, Biomaterials, Microfluidics, Soft Lithography
higher-education
Highest Education Qualification
  • Ph.D.
phd
PhD University
  • National University of Singapore
phd-completion
PhD Completion Year
  • 2015
teaching-experience
Teaching Experience Years
  • 6
research
Research Experience Years
  • 4
Specisubjectalization
Subjects Taught
  • Biomaterials, Biomedical Devices, Genetics, Basic Electronics, Fabrication and Design Thinking
research-domain
Research Domain
  • Mechanobiology, Biomaterials, Microfluidics, Soft Lithography
research-details
Research Details
  • 1. Publications: • S Nalband, P Kiratkar, M Gupta, M Gambhir, S Sonam, F Robert, A A Prince. Ensemble techniques for predictive modeling of leishmanial activity via molecular fingerprints. 2025. BMC Medical Informatics and Decision Making. (https://doi.org/10.1186/s12911-025-03041-4) • S Sonam, L Balasubramaniam, S-Z Lin, YM Yow Ivan, C Jebane, Y Toyama, P Marcq, J Prost, RM Mège, J-F Rupprecht, B Ladoux. Mechanical stress driven by rigidity sensing governs epithelial stability. 2023. Nature Physics. (https://doi.org/10.1038/s41567-022-01826-2) • N Rose, B Estrada Chavez, S Sonam, T Nguyen, G Grenci, A Bigot, A Muchir, B Ladoux, B Cadot, F Le Grand, L Trichet. Bioengineering a miniaturized in vitro 3D myotube contraction monitoring chip to model muscular dystrophies. 2023. Biomaterials. (https://doi.org/10.1016/j.biomaterials.2022.121935) • S Sonam, C Vigouroux, A Jégou, G Romet-Lemonne, C Le Clainche, B Ladoux, RM Mège. Direct measurement of near-nanoNewton forces developed by self-organizing actomyosin fibres bound α-catenin. Biology of the Cell. 2021, 1-9. (https://doi.org/10.1111/boc.202100014) • L Balasubramaniam, A Doostmohammadi, TB Saw, GHN Sankara Narayana, R Mueller, T Dang, M Thomas, S Gupta, S Sonam, AS Yap, Y Toyama, RM Mege, J Yeomans, B Ladoux. Investigating the nature of active forces in tissues reveals how contractile cells can form extensile monolayers. Nature Materials. 2021. 20, 1156–1166. (https://doi.org/10.1038/s41563-021-00919-2) • W Xi*, S Sonam*, TB Saw*, B Ladoux, CT Lim. Emergent patterns of collective cell migration under tubular confinement. Nature Communications. 2017. 8 (1), 1517. (*co-first authors) (https://doi.org/10.1038/s41467-017-01390-x) • W Xi, F Kong, JC Yeo, L Yu, S Sonam, M Dao, X Gong, CT Lim. Soft tubular microfluidics for 2D and 3D applications. Proceedings of the National Academy of Sciences, 2017, 114 (40), 10590-10595. (https://doi.org/10.1073/pnas.1712195114) • S Sonam, SR Sathe, EKF Yim, MP Sheetz, CT Lim. Cell contractility arising from topography and shear flow determines human mesenchymal stem cell fate. Scientific reports. 2016, 6, 20415. (https://doi.org/10.1038/srep2041) • Y Liu, Kenry, Y Guo, S Sonam, SK Hong, MH Nai, CT Nai, L Gao, J Chen, BJ Cho, CT Lim, W Guo, KP Loh. Large-Area, Periodic, Hexagonal Wrinkles on Nanocrystalline Graphitic Film. Advanced Functional Materials, 2015, 25 (34), 5492-5503. (https://doi.org/10.1002/adfm.201502010) • HW Hou, WC Lee, MC Leong, S Sonam, SRK Vedula, CT Lim. Microfluidics for applications in cell mechanics and mechanobiology. Cellular and Molecular Bioengineering, 2011, 4 (4), 591-602. (https://doi.org/10.1007/s12195-011-0209-4) 2. Book Chapters: • Assistive Technology for Neurorehabilitation. S Sonam, P Ranjan. IFNR Textbook of NeuroRehabilitation. 2024. ISBN 978-9390616428 • One-dimensional Polymeric Nanocomposites for Tissue Engineering. S Sonam, S Kumar, S Singh. One Dimensional Polymeric Nanocomposites: Synthesis to Emerging Applications. CRC Books. 2022. ISBN 9781032116211 • Tubular microscaffolds for studying collective cell migration. W Xi, S Sonam, CT Lim, B Ladoux. Methods in cell biology. Elsevier. 2018. 146, 3-21. ISBN 978-0-12-814280-6 3. Conference Presentations: • Fabrication beyond Core Engineering. Invited Talk. AICTE Idea Lab Chief Mentors Conclave. D Y Patil International University. 25th-26th April 2025. Pune. • Cell-cell adhesion affects epithelial monolayer integrity. Invited Talk. International Conference on Biomedical Engineering 2024. December 9th-12th, 2024. Singapore. • Navigating sustainability: Shifting Perspectives. Invited Talk. Sustainability Conclave on Productivity and Green Growth. January 18th, 2024. Pune. • Substrate rigidity based epithelial fracture is driven by intercellular mechanical stress. Invited Talk. Soft Matter Young Investigators Meet. October 14th-16th, 2021. Virtual • Design Thinking in Tissue Engineering. Invited Keynote Address. 8th Bihar Science Conference 2020. An International Conference on Science and Technology. December 3rd-5th, 2020. Patna, Bihar • Intercellular stress mediated epithelial instability on soft hydrogels. Poster presentation. Developmental and Cell Biology of the Future. March 27-29th, 2019. Paris, France • In vitro reconstitution of cell adhesion machinery. Poster presentation. World Congress of Biomechanics 2018. July 8-12, 2018. Dublin, Ireland • Actin organization during collective epithelial cell sheet migration in PDMS microtubes. Oral presentation. EMBO EMBL symposium: Actin in action: from Molecular and Cellular Functions. Sept 7-10, 2016. EMBL Heidelberg, Germany. • Effects of Extracellular Matrix Protein on Shear Stress mediated Stem Cell Differentiation. Poster. 15th International Conference on Biomedical Engineering (ICBME) 2013, Dec 4 – Dec 7, 2013. National University of Singapore, Singapore. • Effects of Shear stress on Stem Cell Contractility and Fate. Poster. The dynamic architecture of cells and tissues. Joint Weizmann and Mechanobiology Institute Conference. Oct 21-24, 2013. Mechanobiology Institute, Singapore. • Effects of Shear stress on Stem Cell Contractility and Fate. Poster presentation. Mechanobiology of Proteins and Cells. Sept 29 – Oct 3, 2013. Mount Desert Island Biological Laboratory, Maine, USA. • 4th Course on Cytoskeleton: Cell Migration and Invasion – 2012. Workshop. April 16 – 20, 2012. Institut Curie, Paris, France. • GEM4 Summer School on Cellular and Molecular Mechanics 2010. Workshop. July 25 – 31, 2010. National University of Singapore, Singapore. 4. Professional Memberships: • Member, Sectional Committee on Brain Computer Interfaces, Bureau of Indian Standards • Member, IET
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